Guillain barre syndrome is a rare and severe autoimmune diseases. Our knowledge of the syndrome has hugely expanded since that time. Imunoterapi adalah terapi spesifik untuk pengelolaan sindrom guillain barre dengan pilihan pengobatan plasmaphereis atau intravena imunoglobulin ivig. The pns nerves connect your brain and spinal cord with the rest of your body. With the widespread eradication of poliomyelitis, gbs is the most common cause of acute and subacute. Guillain barre syndrome israel pdf ppt case reports.
Skenario lembar 1 seorang perempuan,18 tahun dibawa ke unit gawat darurat rsup h. Menurut centers for disease control and prevention cdc, sekitar duapertiga dari orangorang dengan sindrom guillain barre berkembang setelah mereka telah sakit dengan diare atau infeksi saluran pernapasan. As a result, your muscles have trouble responding to your brain. Guillain barre syndrome gbs is a rare, but potentially fatal, immunemediated disease of the peripheral nerves and nerve roots that is usually triggered by infections. Guillain barre syndrome, an overview for the layperson, 9th ed. The purpose of this paper is to provide readers with an understanding of guillain barre and conflictions gbs has with other medical resources and diseases. Kondisi ini mungkin membuat saraf meradang yang mengakibatkan kelumpuhan atau kelemahan otot jika tidak diobati secepatnya. Guillain barre syndrome foundation international 2000. It is characterized by abnormal muscle coordination with poor balance and clumsy walking, weakness or paralysis of the eye muscles, and absence of the tendon reflexes. Normally the immune system attacks any germs that get into the body. Millerfisher syndrome is a rare, acquired nerve disease that is a variant of guillainbarre syndrome. The goals of this multicenter controlled trial were. Most people recover, but it may take six months to two years or more.
Diagnosis and management of guillainbarre syndrome in ten. Damage to these nerves makes it hard for them to transmit signals. Guillain barre syndrome, clinical medicine 2010, vol 1, no 4. Pe is performed at specialized centers and involves removing 36 liters of plasma over several hours and replacing it with preferably albumin or in some cases fresh frozen plasma. No one knows why guillain barre strikes some people and not others, or what sets the disease in motion. A common neurological entity with myriad manifestations milind y. Both sensory and autonomic nerve involvement is seen. Sindrom guillain barre atau biasa dikenal sebagai penyakit gbs adalah kondisi langka yang disebabkan oleh sistem kekebalan tubuh yang menyerang sistem saraf. Doc guillaine barre syndrom alifah f izzah academia. Penyebab, gejala, dan pengobatan sindrom guillain barre. Basically its caused by the bodys immune system mistakenly attacking the peripheral nerves and damaging their myelin insulation. Guillainbarre syndrome gbs is an acute, inflammatory, demyelinating polyneuropathy that nowadays represents the most common cause of flaccid paralysis. Guillain barre syndrome gbs adalah terjadinya suatu masalah pada system saraf yang menyebabkan kelemahan otot, kehilangan reflex, dan kebas pada lengan, tungkai, wajah, dan bagian tubuh lain.
Efficacy of intravenous immunoglobulin in the management of guillain barre syndrome. The diagnosis relies heavily on the clinical impression obtained from the. It occurs usually after an acute infectious procedure. Sindrom guillainbarre gejala, diagnosis, pengobatan. Menurut bosch, sgb merupakan suatu sindroma klinis yang ditandai adanya. Gejala yang biasanya terlihat dalam sindrom ini adalah kelemahan, rasa kebas baal, atau nyeri pada anggota gerak seperti tungkai bawah yang dapat menjalar ke tubuh bagian atas. It is characterized by abnormal muscle coordination, paralysis of the eye muscles, and absence of the tendon reflexes. Gbs can range from a very mild case with brief weakness to nearly devastating paralysis. This leads to weakness, numbness, and tingling, and can eventually cause paralysis. Guillainbarre syndrome is a rare disorder that causes your immune system to attack your peripheral nervous system pns. Penatalaksanaan guillain barre syndrome gbs adalah terapi suportif dengan mencegah dan mengatasi komplikasi yang fatal. Autoimmune disorders occur when the immune system malfunctions and attacks the bodys own tissues and organs.
Parry mengatakan bahwa, sgb adalah suatu polineuropati yang bersifat ascending dan akut yang sering terjadi setelah 1 sampai 3 minggu setelah infeksi akut. Tugas mata kuliah patologi keperawatan tentang penyakit langka guillaine barre syndrom. Adam malik medan oleh karena lemah anggota gerak atas dan bawah. Cdc h1n1 flu fact sheet on guillainbarre syndrome gbs. Sindroma guillainbarre dr iskandar japardi fakultas. Saraf guillain barre syndrome gbs sedangkan pada gbs gejalanya ada kesemutan kebas serta paralisis. Sindroma guillain barre gbs adalah suatu sindrom kumpulan gejala yang menyerang sistem saraf, seperti saraf tepi, saraf tulang belakang, dan saraf otak. Penyebab dari sindrom guillain barre adalah tidak diketahui. Guillainbarre syndrome gbs is a disorder in which the bodys immune system attacks part of the peripheral nervous system. Newswanger, lcdr, mc, usnr, national naval medical center, bethesda, maryland charles r.
Gbs has various subtypes that vary in their pathophysiology. The cause is unknown, but most cases seem to be triggered by a bacterial or viral illness. Guillainbarre syndrome fact sheet national institute of. Mengenal guillain barre syndrome g bs tutiek rahayu dosen jurdik biologi fmipa uny pendahuluan menurut centers of disease control and prevention cdc 2012, guillain barre syndrom g bs adalah penyakit langka di mana sistem kekebalan seseorang menyerang. Clinical correlates of serum anti gt1a igg autoantibodies, j neurol sci 2004. Once originally considered to be only demyelinating in pathology we now recognise both axonal and demyelinating subtypes. Ricardo erazo torricelli pediatric neurologist hospital luis calvo mackenna, chile. Guillainbarre syndrome is not associated with fever, an important fact in differentiating guillain barre from other diseases. Numerous triggering or antecedent events including infections are recognised and gbs is. Guillain barre syndrome gbs atau yang dikenaldengan acute inflammatory idiopathic polyneuropathy aiip atau yang bisajugadisebutsebagai acute inflammatory demyelinating polyneuropathy aidp adalah suatu penyakit pada susunan saraf yang terjadi secara akut dan menyeluruh, terutama mengenairadiks dan saraf tepi, kadangkadang mengenai saraf otak yang didahului oleh infeksi. Diagnosis guillain barre syndrome gbs atau sindrom guillain barre dapat ditegakkan dengan adanya gambaran klinis klasik gejala kelumpuhan secara asenden, kelemahan otot dan hilangnya refleks anggota gerak.
In europe, gbs is the most frequent form of acute peripheral symmetric paralysis since poliomyelitis has almost completely disappeared. The diagnosis relies heavily on the clinical impression obtained from the history and examination, although cerebro. Feelings of tingling and weakness increase in intensity until the muscles cannot be used at all and the patient is almost totally paralyzed. Metode yang pertama adalah pemberian immunoglobulin intravena ivig. View guillainbarre syndrome research papers on academia. It is an autoimmune disease affecting about one to three per 100,000 people a year. Pungsi lumbal untuk pemeriksaan cairan serebrospinal. Guillain barre usually occurs after a respiratory infection, and it is apparently caused by a misdirected immune response that results in the direct destruction of the myelin sheath surrounding the peripheral nerves or. G uillainbarre syndrome gbs consists of a group of neuro pathic conditions characterized by progressive weakness and diminished or absent reflexes. Guillain barre syndrome gbs is a rare immune mediated polyneuropathy that occurs in previously healthy individuals. Find local guillainbarre syndrome resources for the top u.